Symptoms

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SYMPTOMS

10/5/20252 min read

SYMPTOMS PATTERNS

SYMPTOMS PATTERNS

Gilbert’s Syndrome comes with a wide range of possible symptoms. These are the ones I’ve gathered from my own experience, conversations with others who have GS, clinical studies, and various reliable sources. :p

A few of these can also be signs of other conditions that GS may make you more susceptible to—be sure to check out the Susceptibility page for more details! [imo all of these are MANAGABLE]

Symptoms patterns

Jaundice

[yellowing of the skin or eyes] - this is among one of the most common symptoms of GS. This happens when a substance called bilirubin (a yellow pigment made when red blood cells break down) builds up slightly in the blood. You may notice a slight yellow tinge in the whites of your eyes or in your skin. Even though this is a tell tale sign of GS, not everyone with Gilbert’s syndrome develops jaundice. Some people never notice any yellowing at all.

DARK URINE AND CLAY COLOURED STOOL

Bilirubin is a pigment that gives urine and stool their color. In Gilbert’s syndrome, fluctuations in bilirubin levels and intermittent changes in bile flow can result in dark urine or, less commonly, pale, clay-colored stools.

FATIGUE

Common among Gilberts Syndrome people! especially teens

ITCHY SKIN

Itchy skin can sometimes occur in people with Gilbert’s syndrome. This is thought to be related to the accumulation of bilirubin in the skin, which happens when bilirubin levels in the blood rise

PAIN UNDER THE RIBCAGE

Clinical studies show, that people with Gilberts Syndrome have slower gastric emptying, meaning we are FULL quicker and are less hungry in general

BEING CONSTANTLY FULL/ LOSS OF APPETITE

Most likely due to bile sludge- [ i personally get this after eating reaaalllly high amounts of fructose]

woman in black lace brassiere and blue denim jeans
woman in black lace brassiere and blue denim jeans

NAUSEA

This is mostly likely due to the fact that people with Gilbert's Syndrome have a more likely susceptibility to thinks like SIBO or other microbiome dysbiosis or really low stomach acid

GI ISSUES [indigestion]

High bilirubin can cause a mixture of GI symptoms due to the clogged up glucuronidation pathways and extra bilirubin. The gallbladder also can be more sluggish making people with GS more prone to things like SIBO, Candida and other microbiome overgrowths