Triggers

Triggers

Triggers

Triggers

Triggers for Gilbert’s Syndrome can vary from person to person, but here are some of the most common ones people often report.

DEHYDRATION

Not drinking enough fluids can contribute to elevated bilirubin in Gilbert’s syndrome. Reduced fluid intake may slow the clearance of bilirubin from the blood, making mild jaundice or other symptoms more likely during these periods.

FASTING OR SKIPPING MEALS

Periods of fasting or skipping meals can trigger elevated bilirubin in Gilbert’s syndrome. Reduced food intake may alter liver metabolism and bilirubin processing, increasing the likelihood of mild jaundice or other symptoms

ILNESS OR INFECTION

Acute illness or infection can trigger elevated bilirubin in Gilbert’s syndrome. The body’s response to infection can temporarily affect liver function and bilirubin processing, increasing the chance of mild jaundice or related symptoms.

MENSTRUATION

Hormonal fluctuations during the menstrual cycle can affect bilirubin processing in Gilbert’s syndrome. Changes in hormone levels may temporarily reduce the efficiency of glucuronidation pathways, leading to elevated bilirubin and a higher likelihood of mild jaundice or other symptoms.

MEDICATIONS

A lot of medications go through the glucuronidation pathways and NEED the UGT1A1 enzyme to process, since people with Gilberts Syndrome have less of this enzyme, certain medications may fight for the enzymes attention, causing worse bilirubin clearance

BEING A TEENAGER

Sadly, the teenage years come with a wave of new (and not-so-fun) hormones. YAYY! 🎉 For example, estrogen fluctuations can cause bilirubin levels to spike—making symptoms of Gilbert’s Syndrome more noticeable.

Exercise

Heavy exercise can spike your bilirubin [Exercise is good but know that heavy exercise like cardio CAN spike it]